TODAYS PICK (21-07-2010)

Question history: AIIMS 


Maternal serum Alpha-feto proteins are increased in all except?
a)Anencephaly
b)Maternal SLE
c)Multiple pregnancy 
d)Trisomy 18


    Ans:d

    Discussion: reference Meherbansingh 


    Alpha-fetoprotein :
    • Elevated levels are seen in 
      1. open neural tube defect(anencephaly,meningomyelocele) 
      2. Mutiple pregnancy                                                               
      3. Gastroschisis                                                                        
      4. Congenital nephrosis                                                           
      5. Sacrococcygeal keratoma                                                   
      6. Exstrophy of bladder                                                           
      7. underestimated gestation                                                    
      8. Below average maternal weight                                         
      9. Maternal diseases like Hep.ca,SLE                                  
      • Decreased levels are seen in
      1. Downs syndrome                                                              
      2. Trisomy 18                                                                        
      3. Overestimmated gestation                                                
      4. Above average maternal weight                                        
      5. Nonviable gestation.                                                                                                             
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